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AIRMEITH BIOSCIENCE

Why work with us?

The key to any successful pre-clinical research program is a clear understanding of the questions being asked and a carefully planned strategy to address them. Our mission is to deliver high-quality services that accelerate and de-risk early-stage therapeutic development—helping you generate the robust data needed to move confidently toward later development stages

Long term partnerships

We build enduring collaborations, offering comprehensive, value-added services designed to support your goals throughout pre-clinical development.

Operational Excellence

We are committed to precision, quality, and efficiency across all service lines, ensuring your pre-clinical research moves forward seamlessly.

Anticipating customer needs

Development and integration of new services that align with evolving industry and partner requirements.

Our services

In vitro

The first stage of most drug development starts with a simple question in a simple system. We can develop cell models specific to your research question. Our expertise in cell-based assays can assess the efficacy and toxicity of your drug. We offer a full range of lab techniques from PCR, qPCR, ELISA, Western blot, to assays for toxicity, apoptosis, proliferation and metabolic status to investigate mechanisms involved your target or drug of interest.

Transgenic Technologies

Invariably, research programmes are time critical and require precision and quality. Our suite of transgenic technologies including rederivation, cryopreservation, rapid colony expansion ensure the highest welfare standards and scientific excellence in the in vivo model systems we run. We can rederive mice to SOPF status (removal of viruses, bacteria and other endo- or exo- parasites). Cryopreserving mouse models removing unnecessary breeding, risk of disease, erroneous breeding, loss of fecundity or unforeseen disasters including fire and flooding. And in vitro fertilisations allows rapid expansion of mouse colonies to initiate in vivo studies quickly and efficiently.

Novel model generation

Genetically-altered rodents and cells represent an ever-growing link between understanding the cause of human disease and effective therapeutic development. We offer a full range of capabilities to create knockout, conditional, reporter and humanised genetically altered mice and cells in culture, including gene-modification of existing knockouts. Our highly experienced PhD level staff, ensure fast and efficient delivery of customised projects according to your research needs.

Preclinical

STILL UPDATING autoimmune models (EAE, RA), Inflammation (DSS, Obesity), Fertility investigation (embryo sperm development), tumour models (sub-cut cell line, PDX?)

End-to-end management

The key to any successful research project lies in careful planning and an understanding of the limitations of various approaches available i.e. choosing the most suited strategy for your research question. We are happy to provide advice at all stages of your project, whether only considering in vitro investigation as a possible avenue or requiring complete pre-clinical study implementation.

Novel model generation (CRISPR/Cas9)

Genetically-altered animals and cells represent an ever-growing link between understanding the cause of human disease and effective therapeutic development. We offer a full range of capabilities to create knockout, conditional, reporter and humanised genetically altered animals and cells in culture, including gene-modification of existing knockouts. Our highly experienced PhD level staff, ensure fast and efficient delivery of customised projects according to your research needs.

View our work

Exon Skipping in mdx52 mouse brain 2

Gene therapy study – AON 2

Gene tagging 2

Genetic lethality controlled 2